Exercise Physiology
Mohaddeseh Bashtani; Sina Radaei; Rozhan karami; Nazanin Zahra Azizi; Kamian Khazai
Abstract
Background and purpose: Physical activity is effective on the serum level of the monoamine neurotransmitter dopamine and also reduces psychological disorders such as depression. The aim of this study was to investigate the effect of eight weeks of walking on plasma levels of dopamine and the level of ...
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Background and purpose: Physical activity is effective on the serum level of the monoamine neurotransmitter dopamine and also reduces psychological disorders such as depression. The aim of this study was to investigate the effect of eight weeks of walking on plasma levels of dopamine and the level of depression in elderly women with Alzheimer's disease. Method: In this semi-experimental study, 20 women with Alzheimer's disease with an average age of 73.5 ± 7.72 years who were suffering from moderate to severe depression according to the Beck questionnaire with the opinion of a psychiatrist in a targeted manner and the sample available for were selected to participate in the research. The subjects were randomly divided into two equal groups of 10 people, including the experimental group (walking) and the control group (without regular physical activity). The subjects in the walking group exercised on the treadmill for eight weeks three sessions per week and each session lasted 30-45 minutes with an intensity of 60-75% of the maximum heart rate. Before and after the exercise intervention, blood samples were taken from the cubital vein of all participants in a 12-hour fasting state. Serotonin and dopamine levels were evaluated by ELISA method. The results were extracted using the paired t test and covariance at a significance level of 0.5. Findings: 8 weeks of walking led to a significant increase in dopamine levels (p=0.005) and a significant decrease in depression (p=0.001) in the experimental group compared to the control group. Conclusion: It seems that walking can have positive effects on some neurotransmitters and reduce the level of depression in elderly women with Alzheimer's disease.
Exercise Physiology
Mohaddeseh Bashtani; Kamian Khazaei
Abstract
Purpose: The world is getting old. Alzheimer's disease is a progressive disease, which in case of no intervention, this ratio reaches 4 more advanced stages in people over 85 years old. Some methods have shown that they can be effective in preventing and slowing down the course of the disease. The purpose ...
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Purpose: The world is getting old. Alzheimer's disease is a progressive disease, which in case of no intervention, this ratio reaches 4 more advanced stages in people over 85 years old. Some methods have shown that they can be effective in preventing and slowing down the course of the disease. The purpose of this study was to investigate the role of aerobic exercise program on the quality and Lipid profile related to sleep in the elderly with Alzheimer's disease. Method: 22 elderly people with Alzheimer's disease were randomly divided into two groups of 11 people: aerobic exercise and control. The subjects in the aerobic training group practiced three sessions every week for twelve weeks and each session lasted for 45 minutes. The sleep quality of the subjects was evaluated by the Pittsburgh Sleep Quality Questionnaire (PSQI). Lipid profile related to sleep (TG, TC, LDL, HDL) was also measured by blood sampling before and after twelve weeks of aerobic training. Results: The results showed that the sleep quality of the subjects improved by 31% in the Pied Heroi group, which was statistically significant. In addition, there was a significant improvement in the changes of TG (p=0.034), TC (p=0.017), LDL (p=0.006), and HDL (p=0.016) in the aerobic training group. The results of the independent t test also showed that there was a significant difference in sleep quality between the aerobic exercise and control groups. However, no relationship was observed between changes in sleep quality and changes in Lipid variables related to sleep. Conclusion: It can be concluded that twelve weeks of aerobic exercise improves sleep quality along with Lipid profile related to sleep in the elderly with Alzheimer's disease and will be useful as a way to treat sleep problems in the elderly.
Exercise Physiology
Mohaddeseh Bashtani; Parvaneh Rahimi Ghazi; Nazanin Zahra Azizi; Elahe Khodashenas; Bita Hoseinzade; kamian khazaei
Abstract
Purpose: Sleep quality decreases with age, and as a result, sleep complaints are common in the elderly, especially for inactive people with Alzheimer's disease. Therefore, the aim of this study was to investigate the relationship between respiratory indices and sleep quality in active and inactive elderly ...
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Purpose: Sleep quality decreases with age, and as a result, sleep complaints are common in the elderly, especially for inactive people with Alzheimer's disease. Therefore, the aim of this study was to investigate the relationship between respiratory indices and sleep quality in active and inactive elderly women with Alzheimer's disease. Method: In this research, 24 elderly women with Alzheimer's disease (with an average age of 72.3±7.25 years, height 158.23±6.12 cm and weight 70.23±8.12 kg) voluntarily and after obtaining consent, they participated in two active (12 people) and inactive (12 people) groups. Respiratory indices were measured using a Micro Lab Spirometer. The Pittsburgh questionnaire was used to check sleep quality. Independent t-tests and Pearson's correlation coefficient were used to analyze the data. Results: The average score of sleep quality in the active group was significantly lower than the inactive group (p=0.013). Also, the parameters of expiratory volume with pressure in the first second (p=0.046), maximum voluntary ventilation (p=0.021), forced vital capacity (p=0.033), strong expiratory flow 25 to 75% in the active group was significantly higher than the inactive group. Conclusions: According to the results, it seems that sports activity can be an effective factor in improving the quality of sleep and the functioning of the respiratory system in patients with inactive Alzheimer's disease.
