Exercise Physiology
shahab roozbahani; yaghob changizi; mohamad ahadiyan
Abstract
Purpose: Type 2 diabetes is one of the most important metabolic disorders that different societies are facing with increasing prevalence. Aerobic exercises are a common type of exercise that reduces the levels of triglycerides and low-density lipoproteins and regulates blood pressure. The purpose of ...
Read More
Purpose: Type 2 diabetes is one of the most important metabolic disorders that different societies are facing with increasing prevalence. Aerobic exercises are a common type of exercise that reduces the levels of triglycerides and low-density lipoproteins and regulates blood pressure. The purpose of the research is to investigate the effect of 12 weeks of aerobic exercise on fasting glucose and several serum indicators of cardiovascular disease, in women with type 2 diabetes. Methods: In 2023, 20 women who referred to the Hamadan Diabetes Association voluntarily participated as subjects in this research and were randomly assigned to aerobic (10 people) and control (10 people) groups. The exercise program of the aerobic group included 3 running sessions per week with an intensity of 60-70% of the maximum heart rate for 12 weeks. In order to measure fasting blood glucose, glycosylated hemoglobin (HbA1c) and lipid profile [low-density lipoprotein (LDL-c), triglycerides (TG), High-density lipoprotein (HDL-c)], blood sampling was done before and after 12 weeks of exercise program. SPSS software and Kologrov Smirnov and Student's t test were used to check and analyze the data. Results: The results indicated that after 12 weeks of aerobic exercise, HbA1c (P=0/027), LDL-c (P=0/012) and fasting blood glucose (P=0/043) decreased significantly in the aerobic group. But no significant changes were observed in HDL-c and BMI. Conclusion: The results of this research showed that performing aerobic exercises leads to a decrease in HbA1c, fasting blood glucose and improvement in lipid profile, so it can probably be a useful way of treatment and prevention of cardiovascular diseases in type 2 diabetic patients.
Exercise Physiology
Naser Behpoor; Saeid Naeimi; Ahmad Fasihi
Abstract
Purpose: Diabetes mellitus is the most common metabolic problem worldwide, which is associated with hyperglycemia and structural and functional disorders of the nervous system. The aim of the present study was to investigate the effect of endurance training on serum glucose levels, weight changes and ...
Read More
Purpose: Diabetes mellitus is the most common metabolic problem worldwide, which is associated with hyperglycemia and structural and functional disorders of the nervous system. The aim of the present study was to investigate the effect of endurance training on serum glucose levels, weight changes and Like Growth Factor 1 (IGF-1) protein expression in the hippocampus of diabetic rats. Method: For this study, the samples included 48 male Wistar rats (8 weeks old), which were divided into 4 groups: control (C), the diabetes control (DC), diabetes-training (DT) and exercise (T). In order to induce diabetes, streptozotocin injection was used. 5 sessions per week of endurance activity were performed for 6 weeks. 48 hours after the completion of the exercise program, hippocampal tissue was dissected and extracted. ELISA method and one-way variance test were used to analyze the data. Resalts: Based on the results, serum glucose levels decreased after six weeks of endurance training (p=0.001). The amount of IGF-1 in group DC was significantly lower compared to all groups DT, T, and C (P≤0.05). But the DT group had no significant difference with the C and T groups (P=0.210 and P=0.226, respectively). On the other hand, the amount of IGF-1 in group T was only significantly different from group D (P=0.001). The correlation between blood glucose and IGF-1 was significant (p=0.001, r=0.820). Conclusion: Diabetes reduces IGF-1 and hyperglycemia, but exercise moderates the effect of diabetes on IGF-1. Considering the appropriate duration of training and the correlation of this protein with blood glucose, maybe endurance training can reduce the negative effect of diabetes.
Bakhtyar Tartibian; Mehdi Kushkestani; Sohrab Rezaei; Raheleh Baradaran
Abstract
Purpose: Prediabetes refers to a condition where the level of fasting blood sugar reaches 100- 125 mg/dl. The prediabetes pervasiveness is growing throughout the world. The main objective of the present research is the exploration of the body composition and anthropomorphic differences among prediabetes ...
Read More
Purpose: Prediabetes refers to a condition where the level of fasting blood sugar reaches 100- 125 mg/dl. The prediabetes pervasiveness is growing throughout the world. The main objective of the present research is the exploration of the body composition and anthropomorphic differences among prediabetes and normal people for finding the plans for scanning prediabetes and the impact of exercise on it. Method: The present descriptive cross-sectional research conducted on 251 people. The signed informed consents and information of the education, age, exercise etc. gathered. Then, blood glucose tested, and 133 and 118 participants respectively had been chosen for the prediabetes and normal groups. Digital scales, wall stadiometer, tape measure and body composition monitor had been employed to measure anthropomorphic and body composition indices. Results: Total pervasiveness of prediabetes was 52.98% that accounted for 41.03% of the male and 11.95% of the female. Any significant differences didn’t found in the education level, exercise and physical activity between two groups (p>0.05). However, there was a significant difference in the age just in the male group (p=0.043). It found that the prediabetic participants experience visceral fat, BMI, WC, and WHR higher than the normal participants (p=0.037, p=0.010, p=0.000, and p=0.002, respectively) just in the female group. Conclusions: It has been concluded that anthropomorphic and body composition have differences between normal and prediabetes participants; therefore, they may be used as the screening programs. Moreover, it has been suggested that prediabetes can be prevented by controlling anthropometric and body composition indices by exercise.