New Approaches in Exercise Physiology

Effect of 12 Weeks Pilates Exercise on Oncostatin-M And Insulin Resistance In Inactive, Obese Men

Document Type : Research Paper

Author

Dara Latif Saifalddin

Department of Sport Science for Health and Performance, College of Physical Education and Sport Sciences, University of Halabja, Kurdistan region, Iraq

https://doi.org/10.22054/nass.2025.90364.1224
Abstract
Purpose: Obesity and physical inactivity are linked to insulin resistance and chronic low-grade inflammation. Oncostatin-M (OSM), an IL-6 family cytokine, may connect adipose inflammation to metabolic dysfunction. This study examined whether 12 weeks of supervised Pilates alters serum OSM and insulin resistance indices in inactive obese men. Method: In this quasi-experimental study with random allocation, 30 inactive obese men (30–50 years; BMI 30–35 kg/m²) were assigned to Pilates (n=15) or control (n=15). The Pilates group trained three times weekly for 12 weeks; controls maintained their usual lifestyle. Weight, BMI, waist circumference, estimated VO₂max, fasting glucose, fasting insulin, HOMA-IR, and serum OSM were assessed pre- and post-intervention. Mixed ANOVA and paired/independent t-tests were used (p

Keywords

Pilates
Oncostatin-M
insulin resistance
obese men
exercise training
Subjects
New Approaches in Exercise Physiology
Volume 8, Issue 15
June 2026
Pages 25-44

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