Applying aerobic exercise and physical activity as a therapeutic intervention after multiple sclerosis; review of applied methods and therapeutic interventions

Document Type : Review Article

Authors

1 Department of Sport Sciences, Faculty of Humanities, Semnan University, Semnan, Iran

2 PhD Student in Exercise Physiology, Department of Exercise Physiology, Faculty of Sport Sciences and Physical Education, University of Guilan, Guilan, Iran

3 Master's student in Sports Injuries and Corrective Exercises, Department of Physical Education and Sports Sciences, Faculty of Humanities, Islamic Azad University, Karaj Branch, Karaj, Iran

4 Department of Exercise Physiology and Sport Injuries and Corrective Movements, Faculty of Sport Sciences, Ferdowsi University of Mashhad, Mashhad, Iran, Sports Science Research Assistant, Skill National University, Tehran, Iran

Abstract
Multiple sclerosis (MS) is the most common neurodegenerative disease that causes disability in the central nervous system (CNS) as a result of destruction of myelin sheaths. Because myelinated CNS structures deteriorate, nerve signals are transmitted more slowly, leading to deficits in the function of targeted regions (mostly muscles). Physical training, especially aerobic exercise, because of its low-intensity nature, has been widely suggested to treat or control disease symptoms or progression. Here we provide a summary of the recent studies on the therapeutic effects of aerobic exercises on MS outcomes. Based on the reviewed literature, aerobic exercises, in any type, could improve various aspects of MS impairments such as the immune system, oxidative stress, cognition and behavior, fatigue, balance, quality of life… More studies could be done to clear precise effects of aerobic exercise on MS outcomes. The effect of non-aerobic exercise on MS patients can also be investigated in a more specialized manner.

Keywords

Subjects